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High-Risk Reflex Tests
We partnered with Boston Heart Lab to provide the most complete, individualized Coronary Heart Disease (CHD) risk assessment, treatment options for coronary disease, and quick evaluation of therapies to achieve the best possible cardiovascular health of the individual.Patients who are high synthesizers respond very effectively to statins. If the patient is not at their LDL goal the most effective therapy is to increase the dose of the current statin, or switch to a more effective statin; in order of high to low - Rosuvastatin, Atorvastatin, Simvastatin, Pravastatin, and Lovastatin.
High cholesterol absorbers do not respond as well to statins and, if they are not at their LDL goal, are better candidates for the addition of a CAI (Ezetimibe or Zetia) rather than increasing the statin dose. These tests also enable the diagnosis of rare disorders of cholesterol metabolism, such as phytosterolemia and cerebrotendious xanthomatosis, both of which are eminently treatable.
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High Density Lipoprotein (HDL) Fingerprinting - This patented technology assesses how well HDL particles are functioning to help remove cholesterol from the body. We measure the small HDL particles that pick up cholesterol from the artery wall and also the large HDL particles that deliver cholesterol to the liver. Knowing the sub fractions of a patient provides very precise information about heart disease risk and facilitates more targeted treatment. Measuring these particles also assists in determining how well therapy with medications is working in patients.
Lathosterol, Desmosterol, Campesterol, Beta-Sitosterol, Cholesterol - These tests measure cholesterol production and absorption to assist in selecting optimum LDL modifying therapy. They reveal whether monotherapy with a statin or combination therapy with a stain and cholesterol absorption inhibitor (CAI) will be most effective.
